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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2443343eab531d3855bc2b5a171241fbcca6e0da7ab5ca4f5551a6f9b1c6f63f' 
  AND token = 'EgXEreRjt76SByLEnrR5EvaQNTVZ+UZY1nG96M6yWi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}