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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643aec5105e9441cce179fa73d5a8befbc446b944d895e770d3a7e68c9e29279' 
  AND token = '9SbCL5UFy2j/02CkW+JSjcQNW4ZYKRjM0QV6G58wUQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}