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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efb8096bcfb42892984fcbc0c2ebe12fd76ae343f6006773f5c35e83ab41b65' 
  AND token = 'H0NDIsF8icHLxNgc6U5CWiPit+e3YSI16l3VBWAYETg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}