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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678ae2fed149cf99c7201cd201a2bb262b821e1eba5c9d1be8cdb3f9be72be01' 
  AND token = 'dqUQZJvQNyJUSoJMcWK0Z3vRiNOq+2xuK+MJWcm1Oy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}