SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b2a986e0296f19310435635e24cbd575d9a66652ac1b20cadcdb5a5b88df99' 
  AND token = 'ksLXjZRxokgf3sphLxxSIqywO+MwTD5xRglSAN4mGng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}