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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8225d9767da893522523202b56081c6b13143fd1ff3197c61ae7dac3d9ff83fe' 
  AND token = 'kWkoXmsaxkDwS6L1KQ3uQdW64iQtuIZeAzSGq/xqQ30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}