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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6267293652f3b2e2ad0b0ac981f946e67de5443d644289573b066e329be824b' 
  AND token = 'N6ki/HR0kFksPIjZ2eCDS/QudwK8faNE4VFUmx4dsRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}