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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd50db0c219be0c5107707c2c03909714095ba12343c513eec86d4f788c4fc2f3' 
  AND token = 'X4MdCEHqAX4g/WUEOSlRxhztqzvBp1ESw7JbTyoDP6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}