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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a320ae2e1b72039196dcdedaed7e2d952b7a36908273e0ad21a4b7a60ca1224' 
  AND token = 'Done9KyE60WqUyZWbe/Tb89veMuL83V51+mZtcnKAaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}