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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f27b81b2fb943defd909aa9069d51c762bae69777b5c95485081f3f75068271' 
  AND token = '6GW0WxrMV6h9P5oonM7RQ3/1C6o9esEYOlynESkqOxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}