SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f8f5309afe0d073fe85cf4b6b88883fc51ecf16987913d65c3e2d24914a41e' 
  AND token = '0Bqx7nSpzENbT8hA8qzi4LFEP2qVdMyGIaVxp8194+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}