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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1eedcb2b10427e3e4be7a67adafd1340d8c5d81954202c26869ea3d3f6f4281' 
  AND token = 'u5Bt47qEL/cRsOaKW9wkcMlNB+ZrcKflZQ5QRN5rxYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}