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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f27cf66e8803800c4c4ea276f0abd44ad6e8a5e49ac3cad1085acb193d649d' 
  AND token = 'hLiX6p2FSCg+Q+EUXSt3o63ryiZNfIg+sNUR9Oazhsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}