SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a4657d690f646261db4b5f2bdae325b8345fe0923259073fbfbcaf95ac27d0' 
  AND token = 'yvn+VKwSg1whkiXyoa2Gf8VQD89zQvUWFSsVG7AfBrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}