SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3fd1beba591ae9919daf877e194bcf907db1c501deb9291b822df78839309e3' 
  AND token = 'BWdbuy/TSgdd5dScoWEbwP4aAIk/tDb54Bu9K5u9YHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}