SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e86d097fd69727cdc0e83681fd5062eafc768f44be7bcde14d1ee1efe2428e' 
  AND token = 'OnKBVtOqIdkEsEU+vHRW5Pyv1k8cCUs1fZTa6wM6Uew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}