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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0285ba011162ee1555dc773f627e2f47e9708a32c8e7727ee0b62004899e548b' 
  AND token = 'yGGjy9znNFReSiTrYukrmMn6v21UrZtoJDAqjGi/oJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}