SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306676f9cb41f9595bad35b15c57d46523051da12df9f1bde6e18d883c6ed53f' 
  AND token = 'G96ABv0YRY6NnKAhISMBNXtic2XgndDF6Cn5A+WMJi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}