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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e52579b07afd73c6332274d9c86b3f457627c3d9307aedbf491ea7353894a1' 
  AND token = 'V30wsRd1z539bfej/EZ4T+jSgtYvZno/AcooKaxR8M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}