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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4525f0387921fe412564e501113bbdf22ae177ec36876ec35803c8d03f4d50f8' 
  AND token = 'nAe7V3r9qfMCHk4sBoUJTIygnD/Li8UQ+JcvzBF1gsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}