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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43322443ca4f524c98810b61506e67226ebd4d3c9fbe5aeb7cd58ccb76da75d8' 
  AND token = 'bftuYXr+N71E/xYb8pkO8Zsb8RRUQODvJHuLyS7afIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}