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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b75a9c51e4a03ac3460e14c89e662ad1645566fc3e1328d58da78b35f052bc' 
  AND token = 'c6U1MQmLUpg09FWK9e7bF2SBJzJ3aTnq5qYVIZIZDm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}