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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d475e7a072d9d7333a7122c1d26c21b71c224282ccfb68ec458b40603beed09' 
  AND token = 'Pw2PmgK5FiusAnIoisbWVc+nk1A+yADR2E0cntSjgOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}