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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73647e7a51764ebab9aa33b2a780bded23fd83d0a777bd0403b3bd24b180b8ed' 
  AND token = 'zUr5meepv0+PjNVl0hOWIgFd1WGJsGMp0E+KfDfBmLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}