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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e6a4a47b682eccf6fd86d644dadadb7cd3f11e4c9509b259cededca59998d9' 
  AND token = 'Qm7k6YI0UVEmzMwxyn8qBcibAuF1fAdB8mL6W3KIMFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}