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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e6c808b0d975bee079a96ecf0b329eeb74d1155dba4cdfe2d79aea2a68eb00' 
  AND token = 'Zp/mpBC0KwAoLk3KaPJH5R/FApTE1RWeV/TxaZp4amA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}