SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd29ce571247030d6c543ce84740cd7fea855a4caee11dee74085130323e3c6f' 
  AND token = 'HOJMRntxlbAmirS/NVlDykxMg0wj4HUR1DpcFtS6T6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}