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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e860b3d3d79d8e5221cdb1244180851c9688d490708d173afae980c87782a86a' 
  AND token = 'rU5YKpjpRdt4QQbUCpUh1bOdmirWup9WhL6lkLlvlyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}