SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605c1f22904839fdb057bc40099b155e70e46a5967e69fbbb5116e172955b867' 
  AND token = 'R+vSpEaMyI9F+ZT/4ieRXY/LYdJR6TAthM0iMz4LpyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}