SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19a9c059742bd3b24012a1302bd59ea217fc7e20b13f50c2d1f311c3f35844f' 
  AND token = 'gjVFVN0gnVsIqDl1zgH5hROAreyHFiFXmvK5Yk9vdtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}