SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0d3374c79382b8c64630a09c4319e313fc163142fa815488393977ae9c9eed' 
  AND token = 'nnZgGDmJfwWlTazpd0c629Qlm6w0DF4/hpX5+OH0Lkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}