SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '284992d73ac91fc9d4f7577350ca6c2ecbb0909aaca981ec3949805a84d651aa' 
  AND token = 'IHvbIxy/byU3GZeBg+DThbqmDG8rZo51v3a1VQ/Lbuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}