SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '30a409a142d7f707629750d9e8346ec395c097aa788f24d9b97f8d5df90ef611' 
  AND token = 'cYDRqoTsWtkUMNKiCS0fx+B/RMvOrPmQp4WtP019lCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}