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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4255d685d450b0dea4bef86db58e04aeb28e361c3bcc540234aa4fd91b18112' 
  AND token = 'ly0Uqm/7LCNkXB5SNTTHkwo5u6qBvZK5ewZswPgAxtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}