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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5db216f21b0a6894e80fc4bad34b0687e8ba6b476591a75ee330e56dcaf3c2' 
  AND token = '03FYIqqftadoUPfEPJBqem1kgwfk/Wh0/zntyZgp+TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}