SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11b19edee4565c3eb3d13c8e67dd5fa17d5a15b13962ca47ddbe434fcd408470' 
  AND token = 'Vu7S3oM8ACa7ItBTMtFSqjzTFCr6UJKEUhhgLT5XXU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}