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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d21ee44c4e20741b22207550bf194c7d7b3de2adb8daca6582a1e7e1b8ff94' 
  AND token = 'ztx+sdYNyYTEsdXx+4Uw2o3GVPTCPWfKDahi8JfXllc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}