SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bdc37052ea0a51034e6731a613e6cfecdfe3ee5058dfaf24628599e809e8b73' 
  AND token = '4P7/S4rYs46lGC0xaFK2REf5BOd0Iuaio8QWAO3aneA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}