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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc29c0561fcc5ac9c0b0e2314a68c39a449b99d292ba17217a8d286ab2c66b47' 
  AND token = 'JRdw8X9tA/hMdFkcrgQqD3TmivNOU7BOx6HKsHpZhbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}