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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd954de84d866d27514c7b91fda00f82bdf82500b3797c050077c5dab7b3a4385' 
  AND token = '8Zt11SanzVRFPav6hLnHhNNW7kLfHdFQmlgs3dZ5XYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}