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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76aefd37bd133a71aee43992a339d1b94bc483a62f2450dbffea98c6d8f645f2' 
  AND token = 'N50ZMyQ+ULdwvqLMVLL1g1mhW0u1STNbBgmuOhwpUtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}