SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba7d4a5f1b3f27c83b818ea3566dd3228bef9e7e06d977d320cc185b2ce66201' 
  AND token = 'ijCe43IZOS89gpMcCuz/GTVkI9/4ooR/PnTlO+gJnvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}