SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3d0c63e4649561f7c72a0396705779bc0ffdc263b77bbab984bcc6705ae688' 
  AND token = '8KO1Ws8lwM8oPq5mib44CkRXQ3eFgcKZs+Fh6kMG6gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}