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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac0e70357c8c41680e295f32e264c41cdccaf220bd670222784c949c1cdc67d' 
  AND token = 'JuvkR7dqCk3qkNH9kdKqm+atRfTjNCZebo5iakHUWVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}