SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ce4ec00b43c3116b764d70055b2f583d799a9cdba1d06bffc88a87c0ba8a22' 
  AND token = 'qC2MdfrwM6tpU2SyasXL6VJ+pK4b//BYF8KfTGn5Pf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}