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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e121c3e848cc79f4dbdd3b3a8c115b5a7990d97b3ee564ebff2c874b3abf495f' 
  AND token = 'ss27kwrUNSr0nUjuUCe7yy8Q6REK4Dg1bm7PYnXnCJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}