SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7dbd8e53c0474c529e263c9bfa9f504964ba84158600f7a60efeca93cd95caf' 
  AND token = '5VpgJfUTRStrnG+q88NxBPcg2pEGW93FBpzB08PIsT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}