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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a7884e23cbb88853e3c7551a3285fbbd13be6b488be3d892b91504661f87225' 
  AND token = '/aUOsT3Ydt3fQIGgGE8Y2N1eKk98+QVgU4rlYFvTXlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}