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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c7f2e3e684a8df217a44b75d9c7bbc6d03dcfdd58791fa6b15467912d3d109' 
  AND token = 'V6EgScyPfRAQBAc3ZEgy2Rm2MgxfQy+EgT0ZzEKZVnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}