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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d817958460df2c509542af4b01ea2b84dff3f6b598a5d2c94baca9b2e9a4d8' 
  AND token = '6jxMMS6pqsVmoVCB8c5cWS4n1iE2KHxG1fs4CVQ0YIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}